Investigations for malignancy in patients diagnosed with VTE


All patients should have a full history and examination. Patients with any concerning symptoms or signs should have targeted further investigations to investigate for an underlying cancer.

A recent large randomised controlled trial has demonstrated that routine screening with CT of the abdomen and pelvis did not provide a clinically significant benefit.

The following further investigations are recommended:

  • chest X-ray, and if not performed in the past year:
    • breast examination
    • ensure cervical smear up to date
    • PSA in men over 40 years of age