Chlamydia Trachomatis/Urethritis

Warning

If positive for chlamydia, treat index case, refer to GUM to initiate partner notification, testing and treatment.

Advise patient with chlamydia to abstain from sexual intercourse until doxycycline is completed or for 7 days after treatment with azithromycin (If urethritis -14 days after treatment started and until symptoms resolved).

Test of cure (TOC) not routinely recommended following completion of treatment unless: pregnant; rectal infection; poor compliance with treatment; lymphogranuloma venereum (LGV). Perform TOC no sooner than 3 weeks (DNA may be detected by NAAT for 3-5 weeks following treatment). Alternatively, where LGV is suspected (higher risk in HIV positive individuals, proctitis) consider treating with three weeks of doxycycline.

Test for re-infection at 3-6 months following treatment if <25 years; or consider if >25 years and high risk of re-infection.

Drug details

Drug

First line:
Doxycycline

Dosage

100mg

Duration

twice daily for 7 days

Drug

Alternative required (pregnant or breastfeeding): Azithromycin

Dosage

1g

500mg

Duration

single dose then

once daily 2 days (total 3 days)

Editorial Information

Last reviewed: 18/05/2022

Next review date: 18/05/2025

Author(s): NHS Lanarkshire Antimicrobial Management Committee, Dr Dundas, Dr Hylands, S McCormick, Heather Boyle.

Version: V1

Approved By: AMC; ADTC

Reviewer name(s): NHS Lanarkshire Antimicrobial Management Committee.

Document Id: June 2022