PCSK9 inhibitors and modulators (Formulary)

ALIROCUMAB

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Solution for injection pre-filled pen 75mg/mL, 150mg/mL (specialist use only)

Dosage:

EVOLOCUMAB

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Solution for injection pre-filled pen 140mg/mL (specialist use only)

Dosage:

  • By subcutaneous injection, 140mg every 2 weeks, alternatively 420mg every month, administered into the thigh, abdomen or upper arm.
  • See SMC advice 1148/16.
  • Homecare is the preferred option - contact nhsh.homecare@nhs.scot

INCLISIRAN

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Solution for injection in pre-filled syringe 284mg (hospital use only)

Dosage:

  • For patients under lipid clinic who are eligible for PCSK9 inhibitors but who have failed treatment with them due to side effects.
  • See SMC advice 2358.
  • Homecare is the preferred option - contact nhsh.homecare@nhs.scot

 

Editorial Information

Document Id: F052