Vasoconstrictor sympathomimetics (Formulary)

ADRENALINE/EPINEPHRINE

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Injection 1 in 1,000 5mg/5mL (for specialist use in High Dependency Units only)

EPHEDRINE

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Injection 30mg/10mL (hospital use only)

METARAMINOL

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Injection 10mg/mL (hospital use only)

MIDODRINE

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Tablets 2·5mg, 5mg, 10mg (specialist initiation / recommendation only)

Dosage:

Severe orthostatic hypotension, initially 2·5mg three times daily increased weekly according to response up to a maintenance dose of 10mg three times daily. The last dose should be taken at least 4 hours before bedtime.

NORADRENALINE/NOREPINEPHRINE

Important: Therapy notes

Risk of medication errors with noradrenaline/norepinephrine 0·08mg/mL (4mg/50mL) solution for infusion. Healthcare professionals should be aware of the differences in strength and presentation between noradrenaline/norepinephrine products – manufacturer advises noradrenaline 0·08mg/mL (4mg/50mL) solution for infusion must not be diluted before use and should only be used for the ongoing treatment of patients already established on noradrenaline therapy, whose dose requirements are clinically confirmed to be escalating.

Risk Minimisation Materials

Important: Formulation and dosage details

Formulation:

Injection 1 in 1,000, noradrenaline base 4mg/4mL (hospital use only)

PHENYLEPHRINE

Important: Therapy notes

Important: Formulation and dosage details

Formulation:

Injection 1mg/10mL (hospital use only)

Editorial Information

Document Id: F061