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Oral ibuprofen and diclofenac (Drugs used in rheumatic diseases and gout) may also be used in ureteric colic.

DICLOFENAC

Important: Therapy notes

MHRA advice: Non-steroidal anti-inflammatory drugs (NSAIDs): potential risks following prolonged use after 20 weeks of pregnancy (June 2023) (www.gov.uk).  

  • Abscesses and local necrosis at the injection site have been reported with diclofenac intramuscular injection. Always consider alternative routes of administration and follow manufacturers’ instructions for intramuscular administration with care.

Important: Formulation and dosage details

Formulation:

Suppositories 50mg, 100mg

Dosage:

Ureteric colic: by rectum, 50 to 100mg

Important: Formulation and dosage details

Formulation:

Injection 75mg/3mL

Dosage:

Ureteric colic: by deep intramuscular injection, 75mg then a further 75mg after 30 minutes if necessary. Administer intramuscular injections by deep intragluteal injection into the upper outer quadrant. If 2 injections daily are required, use the alternate buttock for the second injection.  Alternatively, 1 ampoule of 75mg can be combined with other dosage forms of diclofenac (tablets or suppositories) up to the maximum daily dose of 150mg.

Editorial Information

Document Id: F248