Musculoskeletal relaxants (Formulary)

Diazepam is used as a musculoskeletal relaxant – see above.
For information on the management of restless legs syndrome refer to guidance.

QUININE SULFATE

Important: Therapy notes

MHRA advice: Quinine: reminder of dose-dependent QT-prolonging effects; updated medicine interactions (November 2017) (www.gov.uk).
MHRA advice: Quinine: not to be used routinely for nocturnal leg cramps (December 2014) (www.gov.uk).

  • Monitor patients closely during the early stages for adverse effects as well as for benefit. After an initial trial of 4 weeks, stop treatment if there is no benefit. Interrupt treatment at intervals of approximately 3 months to assess the need for further quinine treatment.

Important: Formulation and dosage details

Formulation:

Tablets 200mg

Dosage:

For night cramps: 200mg at bedtime

Editorial Information

Document Id: F283